Amit Choudhury

Amit Choudhury

Company: Momenta

Job title: Associate Director


Mode of Nipocalimab Action, PK-PD-Efficacy from Cells to Patients 1:45 pm

Primary mode of action (MOA) of Nipocalimab for autoimmune indications is IgG lowering from blood MOA and PK-PD relationship is consistent in vitro and in vivo (Tg mice, nonhuman primates, and in humans) Nipocalimab demonstrates rapid FcRn saturation-dependent blockade of IgG recycling in in vitro and in vivo studies Nipocalimab demonstrates efficacy in pathogenic antibody-induced…Read more

day: Day Two

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